These medications include estrogens, progesterone, DHEA, pregnenolone and testosterone (prepared in capsules, creams, drops, or gels) that are identical those found in the human body. It is believed that these hormones are safer because they exactly replace those produced by the body itself. The NIH's Women's Health Initiative found in one large trial of over 16,000 women that use of the commercially available conjugated estrogens/progestin (Prempro™) is not advisable after 4-5 years. Many other bio-identical hormone replacement products are also available including pregnenolone, liothyronine, DHEA, and human growth hormone. People (both men and women) use hormone supplements to maintain proper body function. and reverse the effects of aging.