These medications include estrogens, progesterone, DHEA, pregnenolone and testosterone (prepared in capsules, creams, drops, or gels) that are identical those found in the human body. It is believed that these hormones are safer because they exactly replace those produced by the body itself. The NIH's Women's Health Initiative found in one large trial of over 16,000 women that use of the commercially available conjugated estrogens/progestin (Prempro™) is not advisable after 4-5 years. Many other bio-identical hormone replacement products are also available including pregnenolone, liothyronine, DHEA, and human growth hormone. People (both men and women) use hormone supplements to maintain proper body function. and reverse the effects of aging.

Diabetic patients and others often have leg or foot wounds that are difficult to heal. Sometimes, a combination of medications compounded into a gel or cream will aid in healing. These typically include a medicine to improve blood flow (nifedipine), an antibiotic, and a skin protectant. Hemorrhoids are also difficult to treat. Suppositories with anesthetics, anti-inflammatories, and a vasoconstrictor may be used.

Obtaining the correct dosages for very small or very large animals sometimes requires compounding. Also, there are some medications that need to be re-fomulated into gels for animals that refuse oral medications (e.g. cats). There are other medicines that must be compounded because they are no longer commercially available.

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